OPI•AID peer-reviewed publications
4) Intraoperative opioid administrations, rescue doses in the post-anaesthesia care unit and clinician-perceived factors for dose adjustments in adults: A Danish nationwide survey Tran TXM, Wetterslev M, Nørskov AK, Meyhoff CS, Olsen MH, Itenov TS, Mathiesen O, Karlsen APH; OPI•AID Collaborator Group. Acta Anaesthesiol Scand. 2025 Mar;69(3):e70000. doi: 10.1111/aas.70000. PMID: 39971485; PMCID: PMC11839308.
3) Opioids and personalized analgesia in the perioperative setting: A protocol for five systematic reviews.
Karlsen APH*, Sunde PB, Olsen MH, Laigaard J, Folkersen C, Tran TXM, Rasmussen IH, Kjartansdóttir S, Saito A, Andersen MA, Maagaard M, Papadomanolakis-Pakis N, Dalhoff K, Nikolajsen L, Lunn TH, Meyhoff CS, Jakobsen JC, Mathiesen O. ACTA Anaesth Scand 2024 Aug, https://doi.org/10.1111/aas.14508.
2) Minimal important difference in postoperative morphine consumption after hip and knee arthroplasty using nausea, vomiting, sedation, and dizziness as anchors. Karlsen AP, Laigaard J, Pedersen C, Thybo K, Gasbjerg K, Geisler A, Lunn T, Hägi-Pedersen D, Jakobsen J, Mathiesen O. ACTA Anaesth Scand 2024 Feb, https://doi.org/10.1111/aas.14388.
1) The OPI•AID Zone Tool as a composite outcome for postoperative pain management quality - A protocol for an observational pilot study. Karlsen AP, Tran TXM, Mathiesen O, Jakobsen JC, Meyhoff CS, Lunn TH, Olsen, MH. ACTA Anaesthesiol Scand. 2024 April; Epub ahead of print.
Studies leading up to OPI•AID:
7) Minimal clinically important difference, minimal important difference, and effect size: securing
clinical relevance in clinical trials. Laigaard J, Pedersen C, Karlsen AP. British Journal of Anaesthesia 2022 Mar;128(3):e245-e246.
6) Opioid consumption as a core outcome domain in postoperative pain management. Karlsen AP,
Pedersen C, Laigaard J, Mathiesen O. Pain 2022 Jun;163(6):e786-e787.
5) Minimal clinically important differences in randomised clinical trials on pain management aftertotal hip and knee arthroplasty: a systematic review. Laigaard J, Pedersen C, Rønsbo T, Mathiesen O and Karlsen AP. British Journal of Anaesthesia 2021 May;126(5):1029-1037.
4) Patient characteristics in research on pain management after hip and knee Arthroplasty. Pedersen
C, Koyuncu S, Friis CP, Laigaard J, Anhøj J, Mathiesen O and Karlsen AP. Regional Anesthesia & Pain Medicine 2020 Sep;45(9):709-715.
3) Reporting of outcomes in randomised clinical trials on postoperative pain management after hip
and knee arthroplasty: a systematic review. Koyuncu S, Friis CP, Laigaard J, Anhøj J, Mathiesen O
and Karlsen AP. Anaesthesia 2020 feb;76(2) 261-269.
2) Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial. Gasbjerg KS, Hägi-Pedersen D, Lunn TH, ... Jacobsen JS, Mathiesen O. BMJ 2022;376.
1) Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty:The PANSAID Randomized Clinical Trial. Thybo KH, ..., Jacobsen JS, ..., Mathiesen O. JAMA 2019;321(6):562–571.
OPI•AID proceedings:
7) OPI•AID. Karlsen APH. SSAI Pain Medicine, invited speak, Jan 2025.
6) Intraoperative opioid administrations, rescue doses in the post-anaesthesia care unit and clinician-perceived factors for dose adjustments in adults: A Danish nationwide survey. Tran TXM. DASAIM congress, Young Investigator Price Participator, Nov 2024.
5) The AI in OPI•AID. Folkersen C. DASAIM congress, Young Investigator Price Participator, Nov 2024.
4) OPI•AID. Karlsen APH, Olsen MH, Tran TM, Sunde P. Anesthesia Nurse Symposium Rigshospitalet, invited speak, Nov 2024.
3) OPI•AID. Karlsen APH, Olsen MH, Tran TM, Sunde P. DASAIM congress, invited speak, Nov 2024.
2) Perioperative opioid algorithms for indivildualised dosing, OPI•AID. Karlsen APH, Olsen MH, Tran TM, Itenov TS, Lunn TH, Jakobsen JC, Mathiesen O, Meyhoff C. DASAIM congress, Nov 2023.
1) Perioperative opioid algorithms for indivildualised dosing, OPI•AID. Karlsen APH, Olsen MH, Tran TM, Itenov TS, Lunn TH, Jakobsen JC, Mathiesen O, Meyhoff C. Lassendagen Research Conference, Bispebjerg Hospital, Dec 2023.